What is hair loss?
Physiologically, hair loss means losing or thinning hair.
The cell division of the monocyte is not smooth, growth is shortened and the period from resting to the next growing period becomes longer.
Hair cannot grow continuously and falls out, providing continuity to abnormal conditions.
The average hair count is approximately 100,000, of which roughly 55-100 strands are lost per day. Any more than this number is considered abnormal hair loss.
A person’s hair does not grow constantly, but with the cycle of each independent hair follicle, hair growth and shedding are repeated over time. Hair loss is a physiological phenomenon that stops growth after a certain period and repeats growth in the retrograde stage.
The hair cycle is classified as follows
- Anagen : Hair growth stage
- Catagen : Termination of growth, shrinks hair bulb
- Telogen : When dermal papilla ceases activity and hair is held in place
- Return to anagen : Dermal papilla activates and generates new hair, causing shedding of old hair
The cause of Hair loss
- blood circulation
- endocrine disorders
Precursor symptoms of hair loss
Excessive sebum, keratin, erythema, inflammation, dandruff, and seborrheic dermatitis exposed daily to the environment is harmful to the scalp.
If these symptoms are left for a long time, hair follicles are blocked, hair cells are contracted, hair loss is induced, and hair loss will progresses gradually.
- Normal scalp
- Dry scalp
- Oily scalp
- Sensitive scalp
- Seborrheic scalp
- Dandruff scalp
- Hair loss progressive scalp
The mechanism of hair loss
DHT action shortens the lifespan of anagen hair and gradually reducing the number of hairs by expanding the telogen stage, eventually leading to complete hair loss (renewable is impossible at this point)
Progressive mechanism of hereditary hair loss
Hereditary hair loss is the result of the action of 5α-reductase on male hormones, resulting from the interaction of DHT and hereditary depilation receptors, this can be prevented by inhibiting this process.